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“Week 9 Shockwave: Chiefs Lose Two Core Players Right Before Facing the Bills.”QQ

While the Buffalo Bills deal with several injuries of their own, the Kansas City Chiefs are also banged up entering a critical Week 9 matchup.

The Chiefs declared two key starters out for Sunday’s meeting between the Bills and Chiefs, with running back Isiah Pacheco and rookie left tackle Josh Simmons both set to be sidelined due to injury.

Oct 19, 2025; Kansas City, Missouri, USA; Kansas City Chiefs running back Isiah Pacheco (10) runs the ball against Las Vegas Raiders linebacker Devin White (45) during the second half at GEHA Field at Arrowhead Stadium. / Jay Biggerstaff-Imagn Images

Depleted backfield

Pacheco left the Chiefs’ Week 8 win over the Washington Commanders due to a knee injury, and the team subsequently declared him week-to-week, leading to his upcoming absence against the Bills.

Kansas City’s leading ball carrier has recorded a team-high 78 carries for 329 yards rushing and a touchdown while adding 11 receptions for 43 yards and a touchdown. The fourth-year pro has a limited history against the Bills, having totaled two carries for nine yards and added two receptions for nine yards during a 2022 meeting between the two teams.

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